Biomols Science Blog
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Fat-packed: Cayman LNPs deliver Biomolecules to their Target – Part 1
Following the success of mRNA vaccines against COVID-19, few topics in biomedical research have attracted as much attention as nucleic acid...
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Self-Experimentation – When Researchers Become Test Subjects
“With such tricks, one earns a habilitation in a circus, not at a respectable German clinic.” [1] With these indignant words, Ferdinand...
HIV Cure made in Hamburg?
Curing HIV/AIDS is still one of the great medical challenges of our time – but now, for the first time, there might be a chance to...
Lipid-based Drug Delivery Development with Cayman – Part 2
The best-known variant of "lipid-based drug delivery systems" (LBDDS) is the so-called lipid nanoparticle (LNP). As already mentioned in...
The First Therapeutic Use of Penicillin
The Undiscovered Potential Howard Florey and his team of researchers at Oxford University were the first to seriously recognize the...
Henrietta Lacks' Immortal Cells
65 years ago the first immortalized cell line, today known as HeLa, was established.
The First Synthetic Production of Growth Hormone
On January 6, 1971 Berkeley chemists announced the first synthetic production of growth hormone.
The First Human Gene Therapy
On September 14, 1990, Ashanti DeSilva became the first of only two participants in the world's first approved gene therapy trial. The...
Induced Pluripotent Stem Cells
On August 25, 2006 Cell published Kazutoshi Takahashi and Shinya Yamanaka's work on the induction of pluripotency in embryonic and adult...
Invention of the Hybridoma Technology
On August 7, 1975, César Milstein and Georges Köhler published their seminal paper on the production of monoclonal antibodies in continuous...
The Discovery of Insulin
On July 27, 1921, Sir Frederick Banting and Charles Best succeeded in isolating insulin from canine pancreases and thereby discovered the...
The First Ebola Epidemic
On June 27, 1976 Y.G., a storekeeper at the cotton factory in Nzara, South Sudan, suddenly became ill with a high fever, chest pain, and...
The Discovery of AIDS
On June 5, 1981, Michael S. Gottlieb, an immunologist and assistant professor of medicine at UCLA, and Joel Weisman, DO, jointly reported...
The Cure for Scurvy
On May 20, 1747, James Lind, the ship surgeon of the HMS Salisbury, conducted one of the first clinical trials in medical history and...
The First Modern Vaccine
On May 14, 1796, the English physician and scientist Edward Jenner tested the “world’s first vaccine” on the eight-year-old James Phipps.
The Discovery of DNA Polymerase
On April 16, 1956, about 60 years ago, Arthur Kornberg and his team of biochemists were the first to isolate and later characterize the...
The Discovery of Thermus aquaticus
On April 1, 1969, Thomas D. Brock and Hudson Freeze published their discovery and cultivation methods of a new species of thermophilic...
Creutzfeld Jacob Disease and BSE
On March 20, 1996, the government of the United Kingdom first announced the possible connection between the bovine spongiform...